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Chinese Journal of School Doctor

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  • Superintended by Jiangsu Commission of Health
  • Sponsored by Chinese Preventive Medicine Association, Jiangsu Preventive Medicine Association
  • Editor-in-Chief MA Jun
  • Started in 1987
  • Frequency Monthly
  • Postal code 28-163
  • ISSN 1001-7062
  • CN 32-1199/R
  • Published by Chinese Journal of School Doctor
  • Indexed in CAJCED, CJFD, SWIC, CMCC, CMCI ...
About Chinese Journal of School Doctor actively publicizes the policies pertaining to health released by the Communist Party of China, and publishes the latest theories, techniques, approaches and findings pertaining to school medicine timely, so as to enhance the professional levels of school doctors, communicate ...
    2025 Volume 39 Issue 5  
    Published: 20 May 2025
      
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  • Aticle
    DONG Yanhui, JIANG Jianuo, MA Jun
    Abstract ( ) Download PDF ( )   Knowledge map   Save
    School health work serves as a solid foundation for health education and health promotion among children and adolescents, with campus infectious disease prevention and control being a crucial component of this work. With socio-economic development, the predominant issues related to infectious diseases have gradually evolved. Currently, the public health emergencies confronted by primary and secondary schools primarily stem from respiratory infectious diseases (such as influenza, pertussis, and mumps) and gastrointestinal infectious diseases (such as norovirus-induced infectious diarrhea and hand, foot, and mouth disease). In addition, sexually transmitted infections (STIs) such as HIV, gonorrhea, syphilis, and HPV infection among the student population have become increasingly prominent. To address these challenges, multiple departments in China have issued a series of targeted guiding documents aimed at strengthening campus infectious disease prevention and control and enhancing the simultaneous prevention of multiple diseases. Typically, campus infectious disease Control initiatives commence by addressing the three fundamental links in the transmission process of infectious diseases: controlling the source of infection, cutting off the routes of transmission, and protecting susceptible populations. A multi-pronged approach is adopted: In terms of controlling the source of infection, efforts are made to strengthen the monitoring and early warning of infectious diseases to promptly detect and contain outbreaks. Regarding cutting off transmission routes: A hygienic and healthy campus environment is cultivated to reduce opportunities for pathogen proliferation and dissemination. To protect susceptible populations, active promotion of vaccination is undertaken to elevate the immune levels of the student population. Health education is also deepened to enhance the awareness and capabilities of teachers, students, and parents in infectious disease prevention and control. Simultaneously, comprehensive school health services are implemented to safeguard the physical and mental well-being of students. Against the backdrop of the cross-transmission or concurrent prevalence of numerous campus infectious diseases, which severely impact the student population, constructinga multi-disease co-prevention system is imperative to achieve effective prevention and control of campus infectious diseases, thereby safeguarding the healthy learning and growth of children and adolescents.
  • Aticle
    LU Zhenting, LIANG Jinghong, ZHANG Yi, JIANG Jianuo, WANG Ruolin, DONG Ziqi, SONG Zhiying, SONG Xinli, YUAN Wen, QIN Yang, ZHANG Xiuhong, SONG Yi, YANG Tian, DONG Yanhui
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    Objective To analyze the epidemiological patterns of campus infectious diseases in northern China and their factors, and to propose targeted prevention and control strategies for improving school health management system in China. Methods Based on the monitoring data of common diseases and health-related factors among students in Inner Mongolia Autonomous Region from 2021 to 2023, covering 12 leagues and cities and 103 counties (cities, districts), descriptive analysis, chi-square tests, and Wilcoxon rank-sum tests were performed to quantify the associations between health resource allocation (funding, personnel), multi-departmental collaboration policies, and infectious disease reporting rates. Results From 2021 to 2023, tuberculosis exhibited the highest reported incidence rate among Class A and B infectious diseases, followed by brucellosis and viral hepatitis. Within Class C diseases, influenza demonstrated the highest reporting rate, with hand-foot-mouth disease (HFMD) and mumps ranking closely (both>70%). Notable upward trends were observed for pertussis and HFMD (32.1% increase). Correlation analysis further revealed that the total workforce in health administrative departments was inversely correlated with reporting rates of tuberculosis (P=0.041) and brucellosis (P=0.007). School healthcare personnel density significantly correlated with influenza (P=0.006) and syphilis (P=0.001) reporting rates. Among policy-related factors, only syphilis reporting rates were negatively associated with joint interdepartmental policy issuance (P=0.012). Conclusions The prevention and control of campus infectious diseases in northern China requires attention to regional characteristics and resource allocation efficiency. Recommendations include enhancing classroom air quality monitoring, refining vaccination services, and prioritizing brucellosis health education in pastoral areas.
  • Aticle
    ZHAO Heyan, WANG Ruolin, ZHANG Yi, LU Zhenting, DONG Ziqi, SONG Zhiying, DONG Yanhui, MA Jun
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    Objective To analyze the epidemiological characteristics of infectious disease symptoms and the implementation of suspension measures in primary and secondary schools in a district of Beijing, and to provide evidence-based insights for optimizing campus infectious disease prevention strategies. Methods Between February 2023 and February 2025, data were collected from 4 186 primary and secondary school students in a district, Beijing, using a stratified random sampling method. Descriptive statistics and time series analysis were employed to examine the prevalence of symptoms across different categories, school levels, and seasons, as well as the school suspension metrics. Results Fever was the most frequently reported symptom (3 834 cases, 87.1%). Among all symptoms, school suspension measures related to herpes were the most stringent, with a weighted average suspension duration of 9.3 d and an implementation rate of 79.1%. Differences in suspension responses were observed across school levels: In primary schools, the suspension rate for fever cases was 60.5%, compared to 43.2% in secondary schools. For herpes cases, suspension rate reached 86.8% in primary schools, while secondary schools reported only 13 cases, yet related classes still maintained 10 d suspensions. Seasonally, autumn semester fever cases averaged 4.6 d suspensions, exceeding the 3.6 days observed in spring. Conclusions The predominant infectious disease symptom among primary and secondary school students is fever, with herpes posing notable seasonal risks. Primary schools emerged as key targets for prevention and control, while asymptomatic transmission in secondaryschools warrants heightened vigilance.
  • Aticle
    DONG Yanhui, LIANG Jinghong, ZHANG Yi, WANG Ruolin, DONG Ziqi, LU Zhenting, LI Jing, MA Yinghua, SONG Yi, MA Jun
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    This study is grounded in the strategic objectives of “Healthy China” initiative by distinguishing differentiated training objectives for public health professionals (strategic planning capabilities) and school medical personnel (practical operational capabilities). The primary aim is to develop a theoretical framework for the curriculum reform of “Life Skills and Health Education”, in order to enhance the professionalism and effectiveness of infectious disease prevention and control in schools, as well as to improve the practical skills of full-time staff responsible for infectious disease prevention and control. The framework integrates pathogen biology, epidemiology, and emergency management modules, guided by the competency standards outlined in the “School Infectious Disease Prevention and Control Guidance Manual (2024 Edition)”. A progressive curriculum system of “Theory-Virtual-Practice” is formed, incorporating interdisciplinary practical components, such as collaborative home-school quarantine plans and GIS-based outbreak tracing. An innovative “School-Government-Medical” collaborative education mechanism is proposed, alongside the development of digital tools, including the “Campus Norovirus Emergency Response Virtual Platform”. Alignment with the “Regulations on the Emergency Management of Public Health Incidents” is strengthened through competency-oriented assessments. Within the graduate education and teaching system, we will integrate the characteristics of the “Life Skills and Health Education” course, emphasizing a competency-oriented core. Assessment indicators, such as emergency response efficiency and interdepartmental collaboration, will be designed, and practical training modules for close contact tracing and health intervention design in infectious diseases will be optimized in the future.
  • Aticle
    WANG Jia, SU Ke, JIN Song, DONG Huibin
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    Objective To investigate the factors of poor vision among junior-high school students in Xinbei, and to provide references for the development of scientific prevention and control measures. Methods A total of 1 986 students from three junior high schools in Xinbei, Changzhou, were randomly surveyed with a clustered sampling method. Information of their baselines, visual acuity, and refractive status was collected. Both the single factor and multi factor analysis were applied to analyze the results. Results A total of 1 934 final survey questionnaires were collected, with 1 129 male students (58.38%) and 805 female students (41.62%). The average age of the surveyed junior high school students was (14.18±0.81) years old. Univariate analysis indicated that there were statistically significant differences (all P<0.05) in the gender ratio, grades, family history of myopia, continuous near vision behaviors, and daily outdoor exposure between junior-high school students with normal vision and those with poor vision. The logistic multivariate analysis showed that gender, grade, family history of myopia, continuous near vision behavior and daily outdoor exposure were the factors of poor vision among junior high school students (all P<0.05). The proportion of emmetropia, hyperopia, and high myopia among different grades showed statistically significant differences (all P<0.05). Data of astigmatism, mild myopia, and moderate myopia among different grades showed no statistically significant differences (P>0.05). The proportion of male students with emmetropia, hyperopia, and astigmatism was significantly higher than that of female students (all P<0.05). The proportion of moderate and high myopia in male students was significantly lower than that in female students (both P<0.05). There was no statistically significant difference in the proportion of mild myopia between male students and female students (P>0.05). Conclusions The detection rate of abnormal vision among junior high school students in Xinbei District, Changzhou, is significantly high, and myopia is a serious issue. Therefore, it is crucial to strengthen the prevention and control of myopia among junior high school students.
  • Aticle
    MA Weiping, DU Pengying, NIU Gentian, ZHANG Yanhong, ZHU Li, ZHU Huarui, DING Wenqing, ZHANG Ling
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    Objective To analyze the changes of physical health level and overweight and obesity of college students in Ningxia from 2019 to 2023, so as to provide scientific basis for improving the physical health level of the college students. Methods A total of 146 493 college students were selected by random cluster sampling in Ningxia from 2019 to 2023, According to the National Student Physical Health Standard ( revised in 2014 ), the comprehensive score of physical health evaluation was calculated. The difference of physical health levels of college students were analyzed by χ2 test and one-way analysis of variance. The Cochran-Armitage trend test were used to analyze the trend of overweight and obesity of college students. Results From 2019 to 2023, the average height and weight of college students in Ningxia increased continuously, and the fluctuation of physical fitness indexes in 5 years was statistically significant (all P<0.001). The comprehensive scores of physical health of college students were 71.48±7.62, 71.79±7.86, 69.31±8.67, 69.68±9.30 and 72.80±8.47, respectively. In each year, the comprehensive scores of physical health of female students were better than those of male students (all P<0.001), and the differences in the comprehensive scores of physical health of male and female students in different grades were statistically significant (all P<0.001). In the past five years, BMI increased from (21.34±3.31) kg·m-2 in 2019 to (21.51±3.47) kg·m-2 in 2021, and then decreased to (21.22±3.42) kg·m-2 in 2023. The obesity rate increased from 4.49 % in 2019 to 5.38 % in 2021, and then continued to decline to 4.1 % in 2023. The detection rate of overweight and obesity in male students was higher than that in female students in all grades. The detection rates of overweight and obesity in grade 1 male students increased from 15.20 % and 5.78 % to 19.64 % and 10.21 %, respectively (all P<0.05). The detection rates of overweight and obesity in grade 4 female students decreased from 9.28 % and 2.46 % to 6.29 % and 1.52%, respectively (all P<0.05). Conclusions Physical health level of college students in Ningxia is not optimistic. The problem of overweight and obesity is still severe. It is necessary to take corresponding measures to improve their physical health according to the characteristics of students of different genders and grades.
  • Aticle
    TUO Yifei, LEI Yu, GAO Jing, MA Xiaoyan, CHEN Linlin, DING Wenqing
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    Objective To investigate the epidemiological trends of cardiovascular disease risk factors among adolescents in Yinchuan, and to provide scientific basis for mitigating the burden of these risk factors. Methods A multigage stratified cluster sampling was used to select adolescents aged 12-18 years in Yinchuan in 2015, 2017-2018, 2019-2020 and 2023. Questionnaires, physical examinations (height, weight, waist circumference, blood pressure), and laboratory tests (Fasting Plasma Glucose , Total Cholesterol , Triglycerides , High-Density Lipoprotein Cholesterol , Low-Density Lipoprotein Cholesterol ) were conducted to assess cardiovascular risk factors. Chi-square tests were used to analyze differences in detection rates, with Bonferroni correction for multiple comparisons. Trends were analyzed using chi-square trend tests. Results A total of 3 899 students were included. In 2023, the prevalence rates of abdominal obesity, hyperglycemia, and dyslipidemia were significantly higher in boys and girls compared to 2015 (all P<0.05), demonstrating upward trends. The prevalence of hypercholesterolemia and hypo-HDL-cholesterolemia increased significantly from 2015 to 2023 (both P<0.05). Males exhibited higher obesity rates than females in 2015 and 2017 (both P<0.05), while females exhibited higher abdominal obesity rates from 2019 to 2023 (all P<0.05), demonstrating substantially increasing trend (all P<0.001). The multiple risk factor clustering (≥2 factors) reached 36.2% in males and 44.5% in females in 2023 markedly surpassing 2015 levels (both P<0.05), withprogressive increases in risk factor clustering observed longitudinally. By 2023, 36.2% of boys and 44.5% of girls had ≥ 2 risk factors, showing a significant rise from 2015 (both P<0.05). Hyperglycemia prevalence in 2023 was markedly higher than in 2015-2019 (all P<0.05). Girls had higher abdominal obesity rates in 2019 and 2023, reaching 44.9% in 2023. Conclusions From 2015 to 2023, cardiovascular disease risk factors among adolescents in Yinchuan City remains prevalent and shows increasing trends. Active measures should be taken to adjust lifestyle of adolescents to prevent cardiovascular diseases.
  • Aticle
    SU Yali, BAI Xiaolan, LI Xin, ZHAI Dezhong
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    Objective To compare the differences in the positive rates of influenza among children aged 0-14 in Dingxi from 2022 to 2023, and to analyze the risk factors for influenza infection and severe cases in the area. Methods Based on the influenza surveillance data of children aged 0-14 in the hospital from 2022 to 2023, children aged 0-14 with influenza virus infection who were hospitalized in Dingxi People’s Hospital were enrolled as the case group (n=236), while children of the same age group with non-influenza infection who received health checkups were selected as the control group (n=100). The case group was divided into the mild group (n=152) and the severe group (n=84) based on the severity of the disease. Stepwise logistic regression analysis was applied to explore the risk factors for influenza infection and severe cases. Results The positive rates of influenza among children aged 0-14 from 2022 to 2023 were 11.14% and 14.47%, respectively, and the difference was statistically significant (χ2=4.127, P=0.042). The dominant types of influenza were the Victoria and seasonal H3. Stepwise logistic regression analysis showed that a history of COVID-19 infection and respiratory disease were the risk factors for influenza infection (P<0.05). The long duration of fever, white blood cell count, neutrophil count, neutrophil-to-lymphocyte ratio, and comorbid pneumonia were all the risk factors for severe cases (P<0.05). Conclusions Victoria and seasonal H3 types are the dominant types of influenza in 2022-2023. The history of COVID-19 infection and respiratory disease are the risk factors for influenza infection. Meanwhile, long duration of fever, white blood cell count, neutrophil count, neutrophil-to-lymphocyte ratio, and combined pneumonia are the risk factors for severe cases.
  • Aticle
    WANG Li, ZHENG Jie
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    Objective To investigate the oral health-related quality of life (OHRQoL) of medical undergraduates in Fuzhou, and its related factors, and to provide a reference basis for carrying out targeted education in oral health care among undergraduates. Methods A total of 826 medical students from a medical university in Fuzhou were enrolled for a questionnaire survey, with a stratified cluster random sampling by grades. The General Oral Health Assessment Index (GOHAI) was employed to assess students’ OHRQoL. Independent sample t-tests and stepwise regression analyses were conducted to analyze the related factors influencing their OHRQoL. Results The negative impact rate of OHRQoL regarding oral health among 826 medical students was 21.78%. The negative impact rates of oral physiological function, pain and discomfort, and psychological function were 23.8%, 18.92%, and 14.76%, respectively. Four variables of the elevation of grade levels, paying attention to oral health, the use of fluoride toothpaste, and having regular oral examinations were positively correlated with medical students’ OHRQoL (P<0.05). The fitted model could explain 50.3% of the total variation. Conclusions The overall level of OHRQoL of the respondents is moderate. The elevation of higher grades, paying attention to their oral health, use of fluoride toothpaste, and regular oral examinations are the favourable factors for improving OHRQoL.
  • Aticle
    ZHANG Xie, YANG Changjuan, WU Xinkai, XU Qian, ZHI Qian, YANG Lianjian
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    Objective To analyze the epidemiological characteristics of hand-foot-mouth disease in Shapingba of Chongqing from 2016 to 2023, and to provide a basis for the prevention and control of hand-foot-mouth disease. Methods Data of monitoring reports on hand-foot-mouth disease and laboratory pathogen detection of sentinel monitoring in Shapingba during 2016 to 2023, were collected. Descriptive epidemiological methods were applied to analyze the epidemiological characteristics of hand-foot-mouth disease in the area. Results A total of 28 932 cases of hand-foot-mouth disease were reported in Shapingba, with an average annual incidence rate of 285.04/100 000. After the COVID-19 (2020-2023), the average annual incidence rate was 206.37/100 000, which was lower than the incidence rate of 382.60/100 000 before the COVID-19 (2016-2019), showing statistically significant differences (χ2=691.73, P<0.01). Before the COVID-19 pandemic, the hand-foot-mouth disease in this area exhibited an epidemiological characteristic of a bimodal distribution in the year and a higher incidence in even-numbered years. After the pandemic, this pattern shifted to a unimodal distribution within a year and a higher incidence in odd years. The high-risk population of hand-foot-mouth disease mainly consisted of children aged 5 and under, with a higher incidence among boys than girls, and the incidence was higher in urban areas than in rural areas. Before and after the pandemic, other entero-viruses were the dominant strains. Conclusions After the COVID-19 pandemic, the incidence of hand-foot-mouth disease in Shapingba is significantly lower than that before the pandemic. There are remarkable changes in the peak-incidence years and months. Therefore, targeted prevention and control measures should be taken to effectively address the situation.
  • Aticle
    BAO Xiaojuan, ZHANG Lanlan, ZHU Pingping
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    Objective To understand the health status of college students in Guangzhou, and to provide evidence for college health management. Methods A statistical analysis was conducted on the physical examination results of 9 705 freshmen who enrolled at the university from 2020 to 2023, mainly focused on the differences in the prevalence of abnormal results by year and gender. Results There were 9 016 students (92.9 %) with abnormal physical examination results. The prevalence rates of poor vision from 2020 to 2022 were 83.1%, 78.2% and 70.7%, respectively,showing a decreasing trend year by year (χ2=180.29, P<0.05). The prevalence rates of poor vision rebounded in 2023 (84.63%), showing no differences compared with those in 2020 (83.1%) (P>0.05). In 2022 and 2023, there was no significant difference in the prevalence rates of abnormal liver function (15.3%, 16.8%), abnormal renal function (55.6%,57.9%), anemia (2.4%, 2.1%), hyperglycemia (0.6%, 0.7%) and abnormal weight (47.3%, 49.6%) between the two groups (P>0.05). However, these prevalence rates showed statistical differences compared with the copying indicators from 2020 to 2021 (P<0.05). The prevalence rates of hypertension (12.7%) and abnormal electrocardiogram (9.5%) in 2023 were statistically different from those in other years (P<0.05). The prevalence rates of hypertension (13.6%), abnormal electrocardiogram (6.4%), abnormal liver function, and abnormal kidney function (17.6%, 61.7% ) and abnormal weight (65%) in male students were higher than those in female students (P<0.05). The prevalence rates of poor vision (83.3%) and anemia (6.5%) in female students were higher than those in male students (P<0.05). There was no statistically significant difference in the prevalence rates of hyperglycemia between male- and female-students (P>0.05). The prevalence rates of hypertension, abnormal liver function, abnormal kidney function, and high blood glucose showed an increasing trend year by year (P<0.05), while the prevalence rates of anemia and abnormal weight showed a decreasing trend year by year (P<0.05). Conclusions The prevalence rates of abnormal physical examination results of freshmen is relatively high. There are differences in different years and genders regarding poor eyesight, hypertension, abnormal electrocardiogram results, abnormal liver and kidney function, anemia, and abnormal body weight. The university should strengthen health management and formulate targeted intervention measures.
  • Aticle
    ZHENG Xinxin, MO Baoqing, LIU Nana
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    Objective To explore the current situation of professional attitudes of five-year higher vocational nursing students, and its relationships with psychological capital, and to provide a reference for higher vocational colleges to cultivate students’ professional attitudes. Methods In November 2023, a total of 665 students spanning grades 1 to 4 from a higher vocational school in Jiangsu were surveyed, with a stratified cluster random sampling method. The general information questionnaire, the Nursing Professional Attitude Scale, and the Psychological Capital Questionnaire were applied for investigation. Results The average score of professional attitude among five-year higher vocational nursing students was (137.12±20.18). The scores of all dimensions of psychological capital were positively correlated with the professional attitude scores (P<0.05). The results of multiple linear regression analysis indicated that the self-efficacy and optimism dimensions of psychological capital showed significantly positive correlation with the professional attitude scores after adjusting for factors, such as grade levels, reasons for enrollment, academic performance, admiration for nursing predecessor, and the perceived status of nurses (R2=0.344, F=59.080, P<0.001). Conclusions The professional attitude of five-year higher vocational nursing students is at a moderately high level. Higher vocational colleges can improve students’ professional attitude with targeted training programs, thereby promoting the improvement of students’ psychological capital.
  • Aticle
    CAI Jian, DENG Jinwen, HE Lunfa, DENG Chuntuo, YANG Chenjia, GUO Yan
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    Objective To investigate the relationship of unhealthy dietary and insufficient physical activity on depressive symptoms among middle school students in Zhongshan City, and to provide a reference for depression prevention and control in middle school students. Methods From 2021 to 2023, 7 166students were selected from eight designated middle schools in Zhongshan City for questionnaire survey using a stratified cluster random sampling method. The chi-square test (χ2 test) and logistic regression were applied to observe the individual and interactive effects of unhealthy dietary and insufficient physical activity on depressive symptoms. Results The detection rate of depressive symptoms was 23.74% among middle school students in Zhongshan City. Logistic regression analysis showed that both unhealthy dietary and insufficient physical activity were the factors for depressive symptoms. Interaction analysis showed that unhealthy dietary and insufficient physical activity had a synergistic effect. Students with both unhealthy dietary and insufficient physical activity were more likely to suffer from depressive symptoms. Conclusion Unhealthy dietary and insufficient physical activity have a synergistic effect on depressive symptoms in middle school students.
  • Aticle
    JI Caifa, CHEN Wenlong, ZHAO Ziyu, ZHOU Sanji, CHEN Lei
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    Objective To understand the knowledge, attitude, and factors of hematopoietic stem cell donation among undergraduates at Hainan Medical University, and to encourage students to be volunteer donors for the Chinese Marrow Donor Program. Methods In September 2023, a cross-sectional survey was conducted among undergraduates at Hainan Medical University to gather demographic data, as well as information on their knowledge and attitude regarding hematopoietic stem cell donation. Single-factor and multiple-factor analysis were applied using independent samples t-tests and multiple linear stepwise regression approach respectively. Results A total of 1 531 undergraduates were enrolled, yielding an average knowledge score of (9.16±1.64) and an average attitude score of (50.80±10.80). The correct response rate for knowledge related to hematopoietic stem cell donation ranged from 12.3% to 95.0%. Among the undergraduates, those who lived in a town (β=0.321), were of Han nationality (β=0.394), were female student (β=0.212), and majored in medicine(β=0.242) had exhibited significantly higher scores in knowledge regarding hematopoietic stem cell donation (P<0.05). Undergraduates of the Han nationality group (β=1.734) demonstrated significantly higher scores in attitude toward hematopoietic stem cell donation (P<0.05). Conclusions To enhance knowledge dissemination and foster a positive perception and willingness to participate in hematopoietic stem cell donation, tailored publicity and educational strategies targeting specific undergraduate subgroups are recommended. These efforts would provide a scientific foundation for encouraging greater participation among undergraduates in the Chinese Marrow Donor Program.
  • Aticle
    WANG Xiao, GENG Jie, XING Feifei, TONG Jing, DU Yangguang
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    Objective To compare the efficacy of the polyethylene glycol precipitation method and the magnetic bead method in the detection of novel coronavirus (SARS-CoV-2) in municipal sewage, and to provide a theoretical basis for the early monitoring and scientific prevention and control of SARS-CoV-2. Methods The standard curve was obtained by gradient dilution of the SARS-CoV-2 standards. The recovery rate of the polyethylene glycol precipitation method and the magnetic bead method were calculated. Both the χ2 test and the Wilcoxon nonparametric rank-sum test were applied to calculate the detection rate and concentration of the SARA-CoV-2. Results In the spiking experiments, the recoveries of Orf1a/b genes were 3.08% and 18.74% by polyethylene glycol precipitation and magnetic bead method, while those of the N gene were 3.46% and 21.52%, respectively. A total of 414 sewage samples were detected using polyethylene glycol precipitation and magnetic bead method respectively. The detection rates of Orf1a/b genes were 37.92% and 43.24%, respectively, and those of N genes were 63.29% and 67.39%, respectively, which showed no significant differences (Orf1a/b gene:χ2=1.025, P=0.311; N gene:χ2=0.323, P=0.570). The detected concentrations M (P25 ~ P75) of the Orf1a/b genes were 0.70 (0.38 ~ 1.41) copies/mL and 3.01 (1.10 ~ 6.31) copies/mL, respectively, while those of the N gene were 4.43 (2.18 - 12.54) copies/mL and 18.11 (6.77 ~ 50.41) copies/mL, respectively. The differences were all statistically significant (for the Orf1a/b gene: Z=-12.977, P<0.001; for the N gene: Z=-14.821, P<0.001). Conclusions There was no significant difference in the detection rate of SARA-CoV-2 in municipal sewage between the two enrichment methods, but the recovery rate of the magnetic bead method was higher. Both the enrichment methods can provide data support for virus monitoring.
  • Aticle
    MIAO Linying, ZHANG Nana, WANG Mengyuan
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    Objective To carry out a detailed cost calculation for the centralized preparation of three categories medications by the hospital’s Pharmacy Intravenous Admixture Service (PIVAS) in 2023, aiming to provide a scientific basis and decision-making support for the hospital administrators to adjust the charging standard of the dispensing service. Methods The Activity-Based Costing method was applied to refine the detailed cost of dispensing three categories medications in the PIVAS. Results The daily actual cost consumption of the PIVAS was 1 798.2 yuan/day, with labor costs accounting for the largest proportion at 1 231.6 yuan/day (68.5%). The average daily preparation cost for routine medications, antimicrobial drugs, and antitumor drugs was 1 158.0 yuan, 480.6 yuan, and 159.6 yuan, respectively. The calculated unit costs were 1.5 yuan/group for routine medications, 1.8 yuan/group for antimicrobial drugs, and 10.64 yuan/group for antitumor drugs. Conclusions The unit costs for dispensing routine medications and antimicrobial drugs in our PIVAS are relatively close to the charging standards, while the unit cost for antineoplastic drugs is higher yet still below the charging standards. To address the significant cost disparity for antineoplastic drugs, it is imperative to strengthen cost control and management during the preparation process to achieve optimal resource allocation.
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    CHEN Hui, ZHONG Lingchen, CHEN Yongquan
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    Objective To analyze a case of nitrite poisoning incident involving a family of three who suffered from consuming homemade pickled food, and to propose preventive and control measures. Methods On-site epidemiological investigation, sanitary investigation and laboratory testing were applied to analyze and identify the possible sources of contamination during pickled food-making. Results Symptoms of dizziness, palpitations, cyanosis of the lips, and vomiting showed in these three patients (two males and one female). The median time of the incubation period was 60 minutes, and clinical treatment with methylene blue was effective. Excessive levels of nitrites were detected in the patients’ vomit and remaining food samples. Conclusions This was an accidental poisoning with excessive nitrite consumption caused by improper processing and storage. Public awareness and prevention of nitrite knowledge should be enhanced, and food processing and storage should be reasonably standardized to avoid the occurrence of nitrite poisoning incidents.
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    DONG Xihui, TANG Xin
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    Objective To understand the prevalence and trends of common chronic non-communicable diseases among faculty and staff of a university in Beijing from 2019 to 2021, and to provide scientific evidence for further improving health promotion efforts. Methods The physical examination results of the faculty and staff from 2019 to 2021 were collected and statistically analyzed. The detection situation and trends of four common chronic diseases, including overweight/obesity, hypertension, elevated fasting blood glucose (FBG) and dyslipidemia were analyzed using χ2 tests and trend χ2 tests. Results From 2019 to 2021, the detection rates of at least one chronic disease among the faculty and staff at the university was 67.90%, 67.45%, and 67.25%, respectively, showing a upward trend with age (P<0.01). The detection rates among males were all higher than those among females, and all the differences were statistically significant (P<0.01). Among them, the detection rates of elevated FBG (26.4% in 2019, 26.89% in 2020, 23.7% in 2021) showed a decreasing trend year by year (P<0.01). The detection rates of hypertension in 2020 (30.19%) was significantly higher than that in 2019 (27%) and 2021(26.2%). However, the trend test showed no statistical significance (P>0.05). There was no statistically significant difference among the years in the detection rates of overweight/obesity (49.6%, 49.81%, 50.6%) and dyslipidemia (25.9%, 26.42%, 26.19%) (P>0.05). Conclusions From 2019 to 2021, over 67% of the faculty and staff at this university suffered from chronic diseases. Except for the decreasing detection rate of elevated FBG, there was no significant improvement in the detection rates of other chronic diseases. It is necessary to enhance the health awareness in the key populations through lifestyle intervention and other measures, such as personalized health management guidance programs, and to effectively improve the health level of the faculty and staff from the results of different disease types, genders and age groups.