● Article
ZHU Guangkui, ZHUANG Siqi, WANG Kun, LI Weixi, JIANG Rui, ZHANG Jiakun, WANG Xiyu, WU Ling, SUN Yue
Objective To explore the correlations between PM2.5 and PM10 exposure and lung function in primary school students, and to provide a scientific basis for air-pollution prevention and control among children. Methods From 2016 to 2018, during autumn and winter, 467 primary school students were randomly selected from a school in Xuzhou. A mixed effect model was applied to analyze the correlations between PM2.5 or PM10 concentrations and lung function indicators among primary school students, including the forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow (PEF), forced expiratory flow rates at 75% of exhaled FVC (FEF75), and forced expiratory flow rates at 25% of exhaled FVC (FEF25). Results The greatest impact on lung function was observed during lag 0-30. With the increase of PM10 by 10μg/m3, FVC, FEV1, PEF, FEF75 and FEF25 decreased by 14.16 mL (95%CI: -21.99, -6.33), 30.36 mL (95%CI: -39.03, -21.69), 79.38 mL/s (95%CI: -101.16, -57.6), 36.89 mL/s (95%CI: -48.2, -25.58) and 86.95 mL/s (95%CI: -109.63, -64.26),respectively. With the increase of PM2.5 by 10 μg/m3, FVC, FEV1, PEF, FEF75 and FEF25 decreased by 27.21 mL (95%CI: -41.19, -13.23), 63.59 mL (95%CI: -78.97, -48.2), 178.51 mL/s (95%CI: -217.78, -139.25), 79.87 mL/s (95%CI: -99.91, -59.84) and 194.83 mL/s (95%CI: -235.6, -154.05), respectively. For PM2.5 increased by 10μg/m3, FEF25 decreased by 218.92 mL/s in boys, which was higher than that in girls (P <0.05). Conclusions The longer the exposure to PM2.5 or PM10, the greater adverse effects on lung function in primary school students. This suggests the importance of sustained protection against medium-term cumulative exposure to outdoor air pollution for primary school students during the pollution period.