Abstract：Objective To investigate the clinical effect and prognosis of modified radical mastectomy with intercostobrachial nerve preservation for breast cancer. Methods Ninety patients with breast cancer who were admitted to a hospital from January 2017 to July 2018 were enrolled in the study. They were divided into two groups (an experimental group and a control group) according to the random number table, 45 cases in each group. Both groups underwent modified radical mastectomy. The experimental group retained the intercostobrachial nerve during the operation, and the intercostobrachial nerve was not preserved in the control group. The perioperative indicators, postoperative distant metastasis, recurrence, sensory dysfunction, and intercostal and anterior wall paresthesia were investigated and compared between the two groups. Results The time of hospital stay in the experimental group was (7.45±1.29) d, which was shorter than that of the control group, and the difference was statistically significant (t=3.497, P<0.001). There were no significant differences between the two groups in the blood loss, the time of surgery, the number of lymph node dissection, the recurrence rate and the distant metastasis rate (P>0.05). In the experimental group, the scores of sensory dysfunctions were (2.05±0.69) and (2.88±0.83) in 1 month and 3 months after the operation respectively; the areas of intercostal and anterior wall paresthesia were (4.12±0.69) cm2 and (2.42±0.19) cm2 in 1 month and 3 months after the operation respectively. In the control group, the scores of sensory dysfunction were (1.62±0.55) and (2.09±0.71) in 1 month and 3 months after the operation respectively; the areas of intercostal and anterior wall paresthesia were (14.28±2.82) cm2 and (7.95±1.88) cm2 in 1 month and 3 months after the operation respectively, and the differences were statistically significant (P<0.05). Conclusion In the modified radical mastectomy for breast cancer, the retention of intercostobrachial nerve can promote the recovery of patients and shorten the length of hospital stay. It can reduce the abnormal areas of intercostal space and anterior wall, reduce the degree of sensory dysfunction, and it has no significant effect on prognosis.
仲广生. 乳腺癌改良根治术保留肋间臂神经的临床效果及预后分析[J]. 中国校医, 2021, 35(3): 167-168,210.
ZHONG Guang-sheng. Clinical effect and prognosis analysis of modified radical mastectomy with intercostobrachial nerve preservation for breast cancer. Chinese Journal of School Doctor, 2021, 35(3): 167-168,210.
2021, Vol. 35 
