Correlation analysis of sperm concentration, forward motile sperm, normal morphological rate, and sperm DNA fragmentation in patients with non-liquefaction semen
HUANG Yanlan, GUO Tengjie
Department of Clinical Laboratory, Zhangzhou Hospital of Traditional Chinese Medicine, Zhangzhou 363000, Fujian, China
Abstract:Objective To investigate the correlation between sperm concentration, forward motile sperm, normal morphological rate, and sperm DNA fragmentation in patients with non-liquefaction of semen. Methods A total of 100 patients with non-liquefaction semen admitted to our hospital from August 2020 to August 2022 were selected as an experimental group, and 100 men with healthy fertility function during the same period were selected as a control group. The differences between sperm concentration, forward motile sperm, normal morphological rate, and sperm DNA fragmentation index (DFI) between the two groups were compared, and the correlation among sperm concentration, forward motile sperm, normal morphological rate, and sperm DFI was analyzed by Pearson correlation. Results The sperm concentration, forward motile sperm, and normal morphological rates in the experimental group were (40.36±4.25)×106/L, (25.74±3.25)%, and (7.89±1.12%)%, respectively, which were lower than those in the control group: (76.85±7.39)×106/L, (47.89±4.32)%, (22.41±2.89%)%, and the sperm DFI in the experimental group was (29.47±3.42)%, higher than that in the control group: (14.25±1.36)%, and all the differences were statistically significant (t=42.804, 40.973, 46.847, 41.353, all P<0.001). Pearson correlation analysis showed that sperm concentration, forward motile sperm, and normal morphological rate were negatively correlated with sperm DFI (r=-0.485, -0.437, -0.476, all P<0.001). Conclusion The patients with non-liquefaction of semen have low sperm concentration, forward motile sperm and normal morphological rate, high sperm DFI, and the conventional parameters of semen are negatively correlated with sperm DFI, which can provide an important reference for clinical evaluation of male fertility.
黄燕兰,郭腾捷. 精液不液化患者精子浓度、前向活动精子、正常形态率与精子DNA碎片的相关性分析[J]. 中国校医, 2023, 37(12): 925-927.
HUANG Yanlan, GUO Tengjie. Correlation analysis of sperm concentration, forward motile sperm, normal morphological rate, and sperm DNA fragmentation in patients with non-liquefaction semen. Chinese Journal of School Doctor, 2023, 37(12): 925-927.
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